All About Skin Care: tattoo

Wednesday, 19 December 2012

Happy face tattoo does serious work

Dec. 3, 2012 — A medical sensor that attaches to the skin like a temporary tattoo could make it easier for doctors to detect metabolic problems in patients and for coaches to fine-tune athletes' training routines. And the entire sensor comes in a thin, flexible package shaped like a smiley face.

"We wanted a design that could conceal the electrodes," says Vinci Hung, a PhD candidate in the Department of Physical & Environmental Sciences at UTSC, who helped create the new sensor. "We also wanted to showcase the variety of designs that can be accomplished with this fabrication technique."

The new tattoo-based solid-contact ion-selective electrode (ISE) is made using standard screen printing techniques and commercially available transfer tattoo paper, the same kind of paper that usually carries tattoos of Spiderman or Disney princesses. In the case of the sensor, the "eyes" function as the working and reference electrodes, and the "ears" are contacts for a measurement device to connect to.

Hung contributed to the work while in the lab of Joseph Wang, a distinguished professor at the University of California San Diego. She worked there for six months earlier this year under the Michael Smith Foreign Study supplement from NSERC.

"It was a wonderful opportunity," Hung said. She worked directly with Wang, who is well-known for his innovations in the field of nanoengineering and is a pioneer in biosensor technology.

The sensor she helped make can detect changes in the skin's pH levels in response to metabolic stress from exertion. Similar devices, called ion-selective electrodes (ISEs), are already used by medical researchers and athletic trainers. They can give clues to underlying metabolic diseases such as Addison's disease, or simply signal whether an athlete is fatigued or dehydrated during training. The devices are also useful in the cosmetics industry for monitoring skin secretions.

But existing devices can be bulky, or hard to keep adhered to sweating skin. The new tattoo-based sensor stayed in place during tests, and continued to work even when the people wearing them were exercising and sweating extensively. The tattoos were applied in a similar way to regular transfer tattoos, right down to using a paper towel soaked in warm water to remove the base paper.

To make the sensors, Hung and her colleagues used a standard screen printer to lay down consecutive layers of silver, carbon fiber-modified carbon and insulator inks, followed by electropolymerization of aniline to complete the sensing surface.

By using different sensing materials, the tattoos can also be modified to detect other components of sweat, such as sodium, potassium or magnesium, all of which are of potential interest to researchers in medicine and cosmetology.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:

Story Source:

The above story is reprinted from materials provided by University of Toronto.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Amay J. Bandodkar, Vinci W. S. Hung, Wenzhao Jia, Gabriela Valdés-Ramírez, Joshua R. Windmiller, Alexandra G. Martinez, Julian Ramírez, Garrett Chan, Kagan Kerman, Joseph Wang. Tattoo-based potentiometric ion-selective sensors for epidermal pH monitoring. The Analyst, 2013; 138 (1): 123 DOI: 10.1039/C2AN36422K

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

View the original article here

In Rochester, a tale of tainted tattoos: Outbreak highlights new source of infection -- tattoo ink

Sep. 6, 2012 — If you end up with a rash on a new tattoo, you should probably think twice before brushing it off as an allergic reaction or a normal part of the healing process.

A recent study in the New England Journal of Medicine documents 19 cases in the Rochester, N.Y., area -- the largest ever reported -- of tattoos infected with a type of bacteria often found in tap water. Evidence points to a premixed gray ink, the type used in currently popular portrait or photography tattoos, as the culprit.

Mary Gail Mercurio, M.D., a dermatologist at the University of Rochester Medical Center, saw 18 of the 19 individuals infected. She says some people with tattoos have allergies or experience other dermatologic complications, but it's not common. "I've seen people with tattoo-related issues over the years, but never this many: The volume of patients impacted makes this a real public health concern.

"Patients and doctors need to have a certain level of suspicion when they see a rash developing in a tattoo. Many of the patients I saw thought their skin was just irritated and the issue would go away during the healing process. In actuality, they had an infection that needed to be treated with an antibiotic; it wasn't going to go away easily on its own."

The investigation of the outbreak, which was also highlighted in the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report, started with a previously healthy 20-year-old man who had a history of multiple tattoos in the past without any issues. In October 2011, he received a new tattoo on his arm and subsequently developed a persistent, inflamed rash in that area. After learning of his case, the Monroe County Department of Public Health explored the issue and identified 18 other individuals who developed similar rashes after getting tattoos at the same parlor, from the same artist.

Tests conducted at the Medical Center revealed that a specific type of bacteria, Mycobacterium chelonae, was in the patients' skin and led to the red, itchy bumps in their tattoos. Further testing found that a premixed gray ink, which the local artist had bought from a manufacturer in Arizona, contained the same bacteria and likely transmitted it to the skin.

Robert F. Betts, M.D., a long-time infectious disease expert at the Medical Center who treated almost all of the patients, confirmed that the infection was only in the areas tattooed with the gray ink. Also called gray wash, it is used to achieve shading and a three-dimensional quality in tattoos.

According to the local tattoo artist, the manufacturer diluted black ink with distilled water to create a gray color. "This organism, M. chelonae, is found in some water supplies," said Betts. "What probably happened is that the water used to dilute the ink introduced the bacteria into it and the trauma associated with getting the tattoo compromised the circulation to that area of the skin, allowing the organism to enter into the skin and grow."

Betts says that this species of bacteria grows best at around 86 °F, a little bit below normal body temperature, which is approximately 98.6 °F. The skin is cooler than the rest of the body, which may explain why the bacteria flourished in the tattooed areas.

Following the investigation, the CDC issued a nationwide alert about the outbreak and the manufacturer voluntarily recalled the ink. Betts evaluated and treated 16 of the 19 patients with standard antibiotics -- azithromycin and doxycycline -- and everyone improved, although at different speeds based on the extent of the infection.

Both Betts and Mercurio believe that tattoo-associated infections are probably more common than we think and that physicians should think about infectious causes if patients aren't responding to topical or other dermatologic treatments that would typically dispel any sort of allergic reaction to a tattoo.

In addition to Betts and Mercurio, Glynis A. Scott, M.D., Matthew A. Lewis, M.D., and Mark H. Goldgeier, M.D., from the Medical Center contributed to the research. Byron S. Kennedy, M.D., Ph.D., from the Monroe County Department of Public Health was the lead author of the New England Journal of Medicine study. Physicians and scientists from the New York State Department of Health, the CDC and the FDA participated in the research as well.